Author

Luciana Polaco Covre

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de JaneiroORCID 0000-0001-5877-0137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Alessandra Marcia da Fonseca-MartinsiD· 2 shared Daniel Cláudio Oliveira GomesiD· 2 shared Herbert Leonel de Matos GuedesiD· 2 shared Hozany PraxedesiD· 2 shared João Victor Paiva RomanoiD· 2 shared Naiara Carla ManhãesiD· 2 shared Alda Maria Da‐CruziD· 1 shared Alisson Amaral da RochaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Alessandra Marcia da Fonseca-MartinsORCID

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2 papers

Recent·Most cited

Adipose-Derived Extracellular Vesicles Mitigate Experimental Cutaneous Leishmaniasis Through an IL-10 Dependent Mechanism

Douglas Barroso de Almeida, Camila Fernandez, Alisson Amaral da Rocha, Igor Bittencourt dos Santos, João Victor Paiva Romano, Hozany Praxedes, Naiara Carla Manhães, Renata Trabach Santos, Beatriz Toja de Miranda, Luciana Polaco Covre, Alessandra Marcia da Fonseca-Martins, Daniel Cláudio Oliveira Gomes, Fernanda Ferreira Cruz, Tadeu Diniz Ramos, Patrícia R. M. Rocco, Herbert Leonel de Matos Guedes

This study shows that adipose-derived mesenchymal stem cell extracellular vesicles reduce cutaneous leishmaniasis severity through IL-10-dependent immunomodulation without affecting parasite load.

bioRxiv · Feb 3, 2026 · PreprintImmunology

Mice Mucosal Leishmaniasis model shown high parasite load, increased cytotoxicity and impaired IL-10+ cells response

Alisson Amaral Da-Rocha, Júlio Souza dos-Santos, Igor Santos Bittencourt, Douglas B. De-Almeida, Naiara Carla Manhães, Hozany Praxedes, João Victor Paiva Romano, Elias Barbosa da Silva-Júnior, Antônio José da Silva-Gonçalves, Márcia Pereira de Oliveira, Luciana Polaco Covre, Daniel Cláudio Oliveira Gomes, Alda Maria Da‐Cruz, Alessandra Marcia da Fonseca-Martins, Herbert Leonel de Matos Guedes

This study evaluates the immunopathological effects of Leishmania amazonensis infection in BALB/c mice via mucosal and dermal routes, finding higher parasite load and inflammation in the mucosa.

Frontiers in Immunology · Aug 4, 2025Peer-reviewedImmunology