Author

Lakshmipuram S. Swapna

McGill UniversityORCID 0000-0001-5906-7574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:deconvolution· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam James ReidiD· 1 shared Aidan Mark EmeryiD· 1 shared Alan TraceyiD· 1 shared Andrew R. LeachiD· 1 shared Antonio MuroiD· 1 shared Antonio OsunaiD· 1 shared Avril CoghlaniD· 1 shared Benjamin L. MakepeaceiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Adam James ReidORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 22, 2022

Guided-topic modelling of single-cell transcriptomes enables sub-cell-type and disease-subtype deconvolution of bulk transcriptomes

Lakshmipuram S. Swapna, Michael Huang, Yue Li

This paper introduces GTM-decon, a method to deconvolve bulk transcriptomes into cell-type and disease-subtype compositions using single-cell RNA-seq data.

DOI 10.1101/2022.12.22.521640

humanscRNA-seq

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GenomicsNature GeneticsPeer-reviewedOct 29, 2018

Comparative genomics of the major parasitic worms

Avril Coghlan, James Anthony Cotton, Nancy E. Holroyd…·Lian-Chen Wang

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.

562 citationstop 1%

whole-genome sequencingstatistical model

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