Tingting Gong

The paper investigates DNA methylation differences in prostate cancer across African, European, and Asian ancestries, finding ancestry-driven methylation patterns linked to disease aggressiveness in African tumors.

Shiny-SoSV predicts the performance of somatic structural variant detection based on parameters like sequencing depth and variant allele fraction.

This paper reviews eight somatic structural variant callers, evaluating their sensitivity and precision across different SV types, sizes, and sequencing conditions.