Elisha D. O. Roberson

The paper evaluates compression algorithms for reducing cold storage costs in small genomics labs, finding zstandard provides better space savings than gzip.

This study delivers SOD2 mRNA via nanoparticles to mice with abdominal aortic aneurysms, reducing aneurysm expansion and rupture by enhancing antioxidant activity and modulating inflammatory pathways.

The paper identifies rare missense variants in the SH3 domain of PSTPIP1 as significantly enriched in hidradenitis suppurativa patients, suggesting shared genetic risk with PSTPIP1-related syndromes.

The paper uses RNA-Seq to analyze SSc patient and control samples, identifying SPAG17 and SOX9 non-coding RNAs as novel factors in SSc pathogenesis.

The paper analyzes RNA-Seq data from JDM patients to show persistent immune activation in PBMCs even when clinically inactive, with correlations to disease activity scores.

The paper identifies and characterizes CasX genome editing sites across multiple model organisms, showing high site density and exon overlap, suggesting CasX's potential as a universal genome editor.

Motif Scraper identifies degenerate nucleotide motif matches in FASTA files, enabling efficient motif searches across genomes.