Anne Pacquelet

The paper shows that cell proliferation and differentiation in C. elegans intestine are partially coupled through reciprocal interactions, with specific factors controlling cell cycle arrest during differentiation.

This study identifies PAR-4/LKB1 as a regulator of intestinal cell number in C. elegans by restricting endoderm specification to the E lineage, independent of cell proliferation.

This study maps the dynamic localization of brush border components in C. elegans using high-resolution imaging and genome editing, showing dynamic enrichment during microvilli formation and stability afterward.