NeurosciencePharmacological ResearchPeer-reviewed
Tilted striatofugal balance and beneficial effects of facilitating mGlu4 receptor activity in the Fmr1-/- mouse model of Fragile X Syndrome
Mathieu Fonteneau, Claire Terrier, Florian Bolot…·Julie Le Merrer
The paper investigates D1/D2-SPN balance in FXS mice and shows that mGlu4 facilitation rescues social deficits.
DOI 10.1016/j.phrs.2026.109712