Author

Harsimranjit Sekhon

SUNY Upstate Medical UniversityORCID 0000-0001-5970-0499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein design· 3 Assay:protein structure· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Stewart N. LohiD· 3 shared Jeung‐Hoi Ha· 2 shared Anna M. JohniD· 1 shared Maria F. PrestiiD· 1 shared Paige O. MirskyiD· 1 shared Spencer B ProcopioiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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3 shared papersSynthetic Biology

Stewart N. LohORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMar 17, 2025

Next Generation of StayGold-based Adaptable Turn-On Maturation (ATOM) Sensors Targeting PSD95, Gephyrin, and HOMER1 Proteins

Harsimranjit Sekhon, Jeung‐Hoi Ha, Stewart N. Loh

This paper develops ATOM biosensors using mStayGold and mBaoJin to detect PSD95, Gephyrin, and HOMER1 with high specificity and turn-on ratios over 100-fold.

2 citations

protein structureexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 28, 2023

Adaptable, Turn-On Monobody (ATOM) Fluorescent Biosensors for Multiplexed Detection in Cells

Harsimranjit Sekhon, Jeung‐Hoi Ha, Maria F. Presti…·Stewart N. Loh

The paper develops ATOM biosensors that activate fluorescence upon target binding, enabling multiplexed detection of proteins in live cells with high specificity.

1 citation

humanimaging

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Synthetic BiologyCell Reports MethodsPeer-reviewedApr 1, 2022

Engineering Protein Activity into Off-the-Shelf DNA Devices

Harsimranjit Sekhon, Stewart N. Loh

This paper describes the engineering of a DNA-activated protein switch, nLuc-AFF, which can be used as a biosensor for DNA/RNA sequences, serotonin, ATP, and as a computational device processing DNA inputs.

9 citations

protein structureexperimental assay

𝕏 PostBluesky