BioinformaticsbioRxivPreprint
HapBridge: A Methylation-Guided Approach for Correcting Switch Errors and Bridging Phased Blocks in Long-Read Phasing
Hansen Chen, Fan Nie, Feng Luo, Jianxin Wang
HapBridge improves haplotype phasing by correcting switch errors and bridging phased blocks using DNA methylation signals, achieving higher accuracy and contiguity in long-read sequencing.
DOI 10.1101/2025.11.07.687303