Cong Wang

The paper introduces MOFF2, a transferable coarse-grained protein force field that improves simulation accuracy for various protein types and predicts condensate behavior.

The paper uses atomistic simulations to study sequence-dependent conformational landscapes of IDPs, identifying a new metric that captures directional structural differences.

This study reports the formation of symmetrical core-shell biomolecular condensates through programmed tetra-peptide libraries and identifies tryptophan's role in structuring these condensates.