Yumeng Zhang

The paper introduces MOFF2, a transferable coarse-grained protein force field that improves simulation accuracy for various protein types and predicts condensate behavior.

This study uses molecular dynamics simulations to show that spacer heterogeneity in stickers-and-spacers polymers promotes condensation but reduces condensate organization and compositional robustness.

The paper uses a protein language model to identify conserved, disordered motifs in IDRs that are implicated in phase separation and MLO formation.

This study develops a nanopore tweezers platform to track conformational dynamics of West Nile viral NS2B/NS3 protease in real-time and reveals its conformational energy landscape.