Author

Thomas E. Siff

Virginia Commonwealth UniversityORCID 0000-0001-6000-6285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew K. OttensiD· 1 shared Haley E. AdcoxiD· 1 shared Jason A. CarlyoniD· 1 shared Jason R. Hunt· 1 shared Kyle G. RodinoiD· 1 shared Paige E. AlleniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Andrew K. OttensORCID

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1 paper

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedSep 14, 2024

Orientia tsutsugamushi Ank5 directs ubiquitination and proteasomal degradation of NLRC5 to inhibit major histocompatibility complex class I expression

Haley E. Adcox, Jason R. Hunt, Paige E. Allen…·Jason A. Carlyon

This study identifies Ank5 as a bacterial effector that degrades NLRC5 to inhibit MHC class I expression, revealing a mechanism for immune evasion by Orientia tsutsugamushi.

13 citationstop 4%

humanproteomics

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