Georg Widhalm

The paper uses plasma immunopeptidomics guided by mutanomes to detect neoepitopes in solid tumors, finding that cfDNA variant calling sensitivity and MS detection limits constrain plasma-based detection.

QSMxT improves QSM processing by reducing artefacts and requiring minimal parameter tuning through a robust masking and two-pass reconstruction method.

This study maps DNA methylation changes in glioblastoma tumors over time and space, revealing heterogeneity and links to tumor microenvironment and patient survival.