Author

Sophie A. Kirschner

University of OxfordORCID 0000-0001-6018-3505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian Peter BirdiD· 1 shared David A. KellyiD· 1 shared Dina De Sousa· 1 shared Jim SelfridgeiD· 1 shared John C. ConnellyiD· 1 shared Justyna Cholewa-WaclawiD· 1 shared Kashyap ChhatbariD· 1 shared Kyla Brown· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adrian Peter BirdORCID

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1 paper

Recent·Most cited

GeneticsMolecular CellPeer-reviewedFeb 8, 2021

Neuronal non-CG methylation is an essential target for MeCP2 function

Rebekah Tillotson, Justyna Cholewa-Waclaw, Kashyap Chhatbar…·Adrian Peter Bird

This study shows that MeCP2's binding to non-CG methylation, specifically mCAC trinucleotides, is critical for normal brain function, as demonstrated by severe Rett syndrome-like phenotypes in mice with a modified MeCP2 domain.

58 citationstop 4%

mouseDNA methylation

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