Roberto De Gregorio

This paper develops a pacemaker-driven human mini-heart using spatial multi-omics and stem-cell engineering to study cardiac conduction and drug discovery.

This study uses single-nucleus transcriptomics to show that perinatal SERT expression in CA3 pyramidal neurons affects gene expression in specific brain regions, with implications for social and spatial circuit development and autism-related genes.

SAHA creates a multimodal, subcellular-resolution reference atlas of healthy human tissues, revealing spatial organization and disease-associated disruptions across multiple organ systems.