Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations
Daniele Mattei, Andranik Ivanov, Marc van Oostrum, Stanislav Pantelyushin, Juliet Richetto, Flavia S. Mueller, Michał Beffinger, Linda Schellhammer, Johannes vom Berg, Bernd Wollscheid, Dieter Beule, Rosa Chiara Paolicelli, Urs Meyer
This study shows that enzymatic dissociation of brain tissue alters transcriptomic and proteotype profiles compared to mechanical dissociation.
International Journal of Molecular Sciences · Oct 26, 2020Peer-reviewedNeuroscience