Juliet Richetto

Preconceptional social isolation alters inflammatory and transcriptional signalling across the placenta-fetal brain axis

This study shows that prolonged maternal social isolation causes coordinated but distinct molecular changes in placenta and fetal brain, with placental immune and interferon signaling inversely linked to fetal brain cell-cycle processes.

Microglia undergo transcriptional, translational and functional adaptations to dark and light phases in laboratory mice

The paper investigates circadian changes in microglial transcriptional, proteomic, and functional profiles in mice, finding significant differences between light and dark phases and impaired circadian regulation in a neurodevelopmental disorder model.

Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations

This study shows that enzymatic dissociation of brain tissue alters transcriptomic and proteotype profiles compared to mechanical dissociation.