Cancer BiologybioRxivPreprint
A role for YAP-mediated regulation of invadopodia in HNSCC cells
Rachel J. Jerrell, Dayton D. Marchlewski, Aron Parekh
This study shows that YAP nuclear translocation in HNSCC cells increases with ECM rigidity, promoting ROCK2 expression and invadopodia maturation, which enhances ECM degradation.
DOI 10.1101/2024.08.02.606435