Author

Dean C. Pavlick

Foundation Medicine (United States)ORCID 0000-0001-6075-6246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Garrett Michael FramptoniD· 2 shared Aimee L. DavidsoniD· 1 shared Akshay KakumanuiD· 1 shared Amanda B. SpurdleiD· 1 shared Andrej J. Savol· 1 shared Brennan James DeckeriD· 1 shared Callan O'connor· 1 shared Christine N. Serway· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Garrett Michael FramptonORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMar 6, 2026

Cancer genomic profiling predicts pathogenicity of BRCA1 and BRCA2 variants

Olga Kondrashova, Rebecca L. Johnston, Michael T. Parsons…·Amanda B. Spurdle

The paper develops machine learning models to predict pathogenicity of BRCA1 and BRCA2 variants using cancer genomic profiles, improving classification of variants of uncertain significance.

DOI 10.64898/2026.03.05.26347746

humanwhole-exome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 20, 2026

LINE-1 retrotransposition is a recurrent cause of MET exon 14 skipping in cancer

Jennifer A. Karlow, Callan O'connor, Radwa Raed Sharaf…·Garrett Michael Frampton

The paper identifies LINE-1 retrotransposition as a cause of MET exon 14 skipping in cancer, leading to actionable mutations.

DOI 10.64898/2026.02.19.706876

humanwhole-genome sequencing

𝕏 PostBluesky