Author

Elizabeth D. Howell

University of PennsylvaniaORCID 0000-0001-6079-0700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bing HeiD· 2 shared Changya CheniD· 2 shared Joanna M. ToberiD· 2 shared Kai TaniD· 2 shared Nancy A. SpeckiD· 2 shared Peng GaoiD· 2 shared Qin ZhuiD· 2 shared Yasin UzuniD· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersDevelopmental Biology

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2 papers

Recent·Most cited

Developmental BiologyBloodPeer-reviewedMay 12, 2020

Developmental trajectory of pre-hematopoietic stem cell formation fromendothelium

Qin Zhu, Peng Gao, Joanna M. Tober…·Kai Tan

The paper identifies a pre-hematopoietic (pre-HE) stage in mouse embryos and shows RUNX1 regulates the transition to hemogenic endothelium, leading to distinct HSPC populations in intra-arterial clusters.

175 citationstop 1%

mousescRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivNov 26, 2019

Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells

Peng Gao, Changya Chen, Elizabeth D. Howell…·Kai Tan

The paper defines the transcriptomes and epigenomes of key developmental stages of HSC ontogeny in mice and constructs transcriptional regulatory networks using computational methods.

49 citations

mousebulk RNA-seq

𝕏 PostBluesky