Teddy X. Cai

The paper validates diffusion and exchange imaging biomarkers using real-time NMR and optical microscopy in ex vivo neural tissue during perturbations.

This study uses DEXSY NMR to show that steady-state water exchange in neural tissue is primarily passive through the phospholipid bilayer, not via ion-dependent channels.

This paper introduces DEXR, a minimal sampling method for diffusion exchange spectroscopy to efficiently quantify exchange, restriction, and time-dependent diffusion using MR data.

The paper introduces a novel NMR method to measure active water exchange rates in neural tissue, showing it reflects homeostasis and metabolic activity rather than just microstructure.