GenomicsbioRxivPreprint
The ultra-sensitive Nodewalk technique identifies stochastic from virtual, population-based enhancer hubs regulating MYC in 3D: Implications for the fitness of cancer cells
Noriyuki Sumida, Emmanouil G Sifakis, Barbara A. Scholz…·Rolf I. OHLSSON
The paper introduces Nodewalk, a highly sensitive method to analyze chromatin networks, revealing that enhancers around MYC operate in a stochastic, mutually exclusive manner, impacting cancer cell fitness.
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