Genetic Risk of Reticular Pseudodrusen in Age-Related Macular Degeneration: HTRA1/lncRNA BX842242.1 dominates, with no evidence for Complement Cascade involvement
Samaneh Farashi, Carla J. Abbott, Brendan R. E. Ansell…·Melanie Bahlo
Author
Moorfields Eye Hospital NHS Foundation TrustORCID 0000-0001-6131-7640Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Samaneh Farashi, Carla J. Abbott, Brendan R. E. Ansell…·Melanie Bahlo
Panagiotis I. Sergouniotis, Adam Diakite, Kumar Gaurav…·Tomas Fitzgerald
The paper uses an autoencoder to derive retinal phenotypes from OCT images, identifies 118 genetic loci, and shows their relevance to retinal morphology and disease prediction.
Alasdair Warwick, Aroon Dinesh Hingorani, Anthony P. Khawaja…·Amand Floriaan Schmidt
The paper introduces MR-Fish, a method using proteomics and Mendelian randomisation to identify causal relationships between proteins and diseases, finding causal links for several proteins associated with conditions like T2DM and CHD.
Qian Yang, Marina V. Yasvoina, Abraham Olvera‐Barrios…·Marcus Fruttiger
This study identifies early microvascular damage in diabetic retinas before clinical DR diagnosis and finds no spatial correlation between capillary dropout and neural cell loss in the inner nuclear layer.
Cecilia S. Lee, Ariel J. Tyring, Yue Wu…·Aaron Lee
This paper uses deep learning to generate perfusion maps from structural OCT images without expert labels, outperforming clinicians in fidelity.