Brendan R. E. Ansell

Edi-Set-Flow detects differential A-to-I RNA editing in bulk RNA-seq data across tissues and conditions, revealing distinct editing signatures and known protein-recoding events in brain samples.

The paper uses iPSC-derived RPE cells to compare molecular differences between AMD with and without reticular pseudodrusen, identifying distinct pathways and genetic influences.

This study identifies conserved microglial miRNAs across species and their preserved function in demyelination and remyelination.

The paper identifies RNA editing sites in human retinal transcriptomes and links editing QTLs to retinal diseases.

This study identifies unique miRNA-mRNA networks in mouse microglia during CNS development and homeostasis, revealing their role in age-specific functions and disease states.

VIVID is a web tool that visualizes and interprets DNA variants in 3D on protein models to study genetic variation and its association with phenotypes.

The paper presents a new high-quality genome assembly and annotation for Cryptosporidium parvum IOWA, revealing structural and functional insights into its genome and evolutionary relationships with related species.

The paper identifies RNA editing sites in single cortical neurons and links locus 15q11 with psychiatric illness through differential editing in cell types.

This study identifies serine biosynthesis as a key driver of MacTel etiology and progression using statistical genetics methods.

This study characterizes the transcriptome and histone epigenome of Plasmodium vivax sporozoites, revealing transcriptional and post-transcriptional control mechanisms and potential pathways for hypnozoite formation.