Author

Dominique Gauguier

Centre National de la Recherche ScientifiqueORCID 0000-0001-6156-9530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana Luísa NevesiD· 2 shared François BrialiD· 2 shared Jeremy Kirk NicholsoniD· 2 shared Julien ChillouxiD· 2 shared Lesley HoylesiD· 2 shared Marc‐Emmanuel DumasiD· 2 shared Alice R. Rothwell· 1 shared Amandine EverardiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPhysiology

Ana Luísa NevesORCID

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2 papers

Recent·Most cited

PhysiologyNature MetabolismPeer-reviewedDec 8, 2025

Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control

Julien Chilloux, François Brial, Amandine Everard…·Marc‐Emmanuel Dumas

This study identifies trimethylamine (TMA) as a microbial compound that inhibits IRAK4, reducing inflammation and improving metabolic outcomes in high-fat diet conditions.

18 citationstop 3%

mouseproteomics

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Systems BiologybioRxivPreprintDec 15, 2019

Microbiome Determinants and Physiological Effects of the Benzoate-Hippurate Microbial-Host Co-Metabolic Pathway

François Brial, Julien Chilloux, Trine Nielsen…·Marc‐Emmanuel Dumas

This study identifies microbiome determinants of hippurate, a metabolite linked to metabolic health, and demonstrates its protective effects in mice through benzoate-hippurate pathway analysis.

2 citations

mousemetagenomics

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