Chuan Dong

The paper identifies primate-specific genes as more essential in cancer cell lines and shows their increased co-expression in cancer networks.

GageTracker dates gene age using micro- and macro-synteny with high speed and accuracy, outperforming existing tools in alignment quality and speed.

This paper introduces AcrDetector, a tool that identifies Acrs in prokaryotes using six features, achieving high accuracy and demonstrating its effectiveness across species.

CasLocusAnno annotates Cas proteins and loci, classifies them into (sub)types, and outperforms existing tools in accuracy and speed.

The paper develops a computational model using sequence information to predict human gene essentiality, achieving high AUC scores and identifying previously overlooked essential genes.