Author

David Leppert

University Hospital of BaselORCID 0000-0001-6172-801XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Adeline W. J. PohiD· 1 shared Alex M. DickensiD· 1 shared Alexandre LucasiD· 1 shared Andrew J. BaldwiniD· 1 shared Andrew M. GiltrapiD· 1 shared Anu J. AiraksineniD· 1 shared Benjamin CharvetiD· 1 shared Benjamin G. DavisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Adeline W. J. PohORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 12, 2026

Antibody-mediated rescue of endogenous retrovirus-induced damage in the demyelinated central nervous system

Laura Reiche, Joel Gruchot, Benjamin Charvet…·Patrick Kuery

This study shows that anti-HERV-W ENV antibodies reduce neurodegeneration and improve remyelination in a mouse model of demyelination.

DOI 10.64898/2026.06.10.731326

mouseexperimental assay

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Synthetic BiologybioRxivPreprintJan 26, 2025

Isostere 18F-protein post-translational editing enables dynamic tracking of neurodegeneration biomarkers

Nan Yang, Adeline W. J. Poh, Andrew M. Giltrap…·Benjamin G. Davis

This paper introduces a method to track neurodegeneration biomarkers using PET imaging with isosteric protein mimics, revealing spinal fluid dynamics and neuronal loss mechanisms.

2 citations

humanproteomics

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