David J. Glass

The paper determines optimal sample sizes for bulk RNA-seq experiments in mice by analyzing large-scale comparative studies and shows that increasing sample size reduces false positives and improves discovery rates.

This study uses exome sequencing of 628,388 individuals to identify genetic variants associated with clonal hematopoiesis and its health outcomes.

The paper performs exome-wide association studies in large cohorts to identify genetic variants linked to human age, finding new candidates and confirming known ones.

The paper identifies age-related gene expression patterns in multiple rat tissues, revealing early, mid, late, and linear transcriptional changes and their potential pharmacological targets.