Chuan Gao

Genome-wide survey of parent-of-origin specific associations across clinical traits derived from electronic health records

This study identifies parent-of-origin specific genetic associations with clinical traits from EHR in a large population study, finding that PoO effects are often captured by standard models but remain underpowered to detect.

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

The paper identifies novel genetic loci associated with blood pressure that interact with sleep duration across multiple ancestries.

Exome-wide association studies in general and long-lived populations identify genetic variants related to human age

The paper performs exome-wide association studies in large cohorts to identify genetic variants linked to human age, finding new candidates and confirming known ones.

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

The paper identifies 49 novel blood lipid loci associated with gene-sleep interactions in 126,926 individuals across 5 ancestry groups, with gene-short-sleep interactions explaining 4.25% of triglyceride variance.