Precious Chinonyerem Opurum

This study shows a high-fat, high-salt diet induces early MDAKD-like kidney injury in mice, with strain-specific mitochondrial dysfunction and fibrosis.

The paper develops a method to profile mitochondrial function in specific kidney segments from mice and humans under thermodynamic control, revealing segment-specific bioenergetic differences.

This study shows that six months of physical inactivity in C57BL/6J mice on a high-fat diet does not cause chronic kidney disease but leads to early kidney injury markers.