Fabien Campagne

ALK1-BMPRII agonism by clustering bispecific antibodies treats hereditary hemorrhagic telangiectasia

This study develops bispecific antibodies that activate the ALK1-BMPRII pathway, reducing AVMs and improving symptoms in HHT mouse models.

Establishing reference samples for detection of somatic mutations and germline variants with NGS technologies

The paper establishes reference samples with high-coverage whole-genome sequencing to create truth sets for somatic mutation and germline variant detection using NGS technologies.

GenotypeTensors: Efficient Neural Network Genotype Callers

GenotypeTensors evaluates neural network genotype callers using semi-supervised approaches, achieving high F1 scores on benchmark datasets.

Training Genotype Callers with Neural Networks

The paper introduces software for training deep learning models to call genotypes from sequencing data, showing high accuracy with limited training data.

CONTINUATION: Evaluation of adaptive somatic models in a gold standard whole genome somatic dataset

The paper evaluates adaptive somatic mutation models using a real dataset and finds that semi-simulation improves model performance on real data.

NextflowWorkbench: Reproducible and Reusable Workflows for Beginners and Experts

NextflowWorkbench simplifies creating reproducible workflows for both beginners and experts by combining a graphical interface with Nextflow scripting.

MetaR: simple, high-level languages for data analysis with the R ecosystem

MetaR is a simple data analysis language for biologists that enables beginners to perform tasks like differential expression analysis and heatmap creation in under 2 hours.