Co-transcriptional Phase Separation of Nucleic Acids at Membrane Surfaces
Adam Mamot, Thuy An Nguyen, Yusuf Qutbuddin, Svetozar Gavrilović, Viktoriia V. Belousova, Souvik Basak, Jan-Hagen Krohn, Nastasja Kaletta, Petra Schwille
The paper shows that transcription in confined membrane-bound systems causes RNA phase separation, which is counteracted by translation factors.
bioRxiv · May 3, 2026 · PreprintBiochemistry