Cell BiologyJournal of Cell SciencePeer-reviewed
The phosphorylation of Pak1 by Erk1/2 for cell migration requires Arl4D acting as a scaffolding protein
Ting-Wei Chang, Ming‐Chieh Lin, Chia‐Jung Yu, Fang-Jen Scott Lee
This study identifies Arl4D as a scaffolding protein that recruits Erk1/2 and Pak1 to the plasma membrane, enabling their phosphorylation and cell migration.