Pharmacology & ToxicologybioRxivPreprint
On the utilisation and characterisation of external biotransformation systems in in vitro toxicology: a critical review of the scientific literature with guidance recommendations
Sebastian Lungu-Mitea, Matilda Stein Åslund, Inska S. Reichstein…·Klára Hilscherová
This paper reviews biotransformation systems in in vitro toxicology, identifies methodological issues, and provides guidance to improve their reliability and integration into regulatory assessments.
DOI 10.1101/2025.09.23.677684