Author

Joachim Heberle

Freie Universität BerlinORCID 0000-0001-6321-2615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:imaging· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Abhishek SirohiwaliD· 1 shared Aleksandra SoleckaiD· 1 shared Amedea PerfumoiD· 1 shared Ana P. Gámiz‐HernándeziD· 1 shared Andreas ElsaesseriD· 1 shared Anna KoczurowskaiD· 1 shared Antonia FurreriD· 1 shared Ayesha Asghar· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiophysics

Abhishek SirohiwalORCID

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4 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 6, 2026

Covalent bond formation caught in a LOV photoreceptor

Bence Olasz, Guillaume Gotthard, Probal Nag…·Przemysław Nogły

This paper resolves the mechanism of covalent bond formation in a LOV photoreceptor using time-resolved crystallography and spectroscopy, revealing a water-mediated proton transfer that accelerates the reaction by fourteen orders of magnitude.

DOI 10.64898/2026.08.02.742302

structural biologyexperimental assay

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedMay 7, 2026

Low-barrier hydrogen-bond powers long-range radical transfer in the metal-free ribonucleotide reductase

Abhishek Sirohiwal, Juliane John, Yury Kutin…·Ville R. I. Kaila

This study identifies a low-barrier hydrogen bond as the key to long-range radical transfer in metal-free ribonucleotide reductase.

DOI 10.1073/pnas.2529856123

statistical modelexperimental assay

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BiophysicsMeasurement Science and TechnologyPeer-reviewedJan 19, 2026

Separate-scan atomic force microscope for fast infrared scattering-type scanning near-field optical microscope

Yusuke Sakiyama, Santiago H. Andany, Georg Ernest Fantner, Joachim Heberle

The paper introduces a separate-scan AFM system integrated with BI-sSNOM to enable faster imaging of biomolecules in aqueous solutions.

1 citation

imagingexperimental assay

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BiophysicsSmallPeer-reviewedMay 6, 2024

Stable Isotope Probing-nanoFTIR for Quantitation of Cellular Metabolism and Observation of Growth-dependent Spectral Features

David J. Burr, Janina Drauschke, Katerina Kanevche…·Andreas Elsaesser

This paper introduces SIP-nanoFTIR to quantify single-cell metabolism and observe growth-dependent spectral features in bacteria.

6 citations

bacteria (other)imaging

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