Paul M. Kulesa

The paper uses an agent-based model to simulate how Trail, Colec12, and Dan confine cranial neural crest cells to stereotypical migration pathways in vivo.

The paper identifies conserved and divergent transcriptional signatures in neural crest cells across chick and mouse embryos during migration.

The paper identifies critical genes for neural crest and cancer cell invasion using high-throughput screening and deep learning analysis.

The paper uses single-cell RNA sequencing to analyze branchial arch development in chick embryos, identifying novel cell type markers and a conserved transcriptional signature of invasive neural crest cells.

The paper investigates the role of Aquaporin-1 in neural crest cell migration, finding it affects speed, direction, and filopodia stability through interactions with MMPs and pFAK.

The paper investigates dynamic feedback between tissue growth and neural crest cell migration during chick head morphogenesis using time-lapse imaging, modeling, and perturbations, revealing its role in robust craniofacial development.