Anne C. Skeldon

The paper mathematically extends the two-process model of sleep regulation to include light effects, enabling quantitative predictions of sleep and circadian interventions.

The paper develops a model to integrate circadian and sleep-wake influences on gene expression, revealing tissue-specific regulatory effects and desynchronization after sleep deprivation.

This paper presents a mathematical analysis of light-sensitivity challenges in assessing the human circadian pacemaker's intrinsic period, showing that dim light may affect results more than previously thought.

This paper introduces a model to distinguish between endogenous and exogenous factors affecting sleep timing using longitudinal data and personalized mathematical modeling.

The paper uses compartmental models from epidemiology to study excitation-inhibition imbalance in epilepsy, showing how dysfunction in inhibitory mechanisms can lead to seizures.

The paper compares two fatigue risk models, HSE Fatigue Risk tool and SAFTE, using data from a construction project, finding they give similar predictions but SAFTE better captures fatigue development during shifts.