Maxime Jan

The paper develops a model to integrate circadian and sleep-wake influences on gene expression, revealing tissue-specific regulatory effects and desynchronization after sleep deprivation.

The paper evaluates the impact of reference bias on transcriptome and eQTL analysis in mouse genetic studies and proposes improved reference strategies.

This study examines how sleep deprivation affects gene expression and chromatin accessibility in mice, revealing long-term genomic regulatory changes.

The paper presents a multi-omics digital research object for studying sleep regulation in mice, integrating diverse datasets and analytics to enhance data reusability and reproducibility.