Author

Ryan Silk

Institute of Genetics and CancerORCID 0000-0001-6421-1294Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ryan Silk1 paper · Institute of Genetics and Cancer;

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ailith EwingiD· 1 shared Alan W. StittiD· 1 shared Alhafidz HamdaniD· 1 shared Alison M. MeynertiD· 1 shared Andrew Victor BiankiniD· 1 shared Athena MatakidouiD· 1 shared Brian Andrew DoughertyiD· 1 shared Brian McDade· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Ailith EwingORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 1, 2025

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Ailith Ewing, Alison M. Meynert, Ryan Silk…·Colin A M Semple

The paper identifies two divergent structural variation trajectories in HGSOC that impact patient survival and reveals novel candidate driver genes and mtDNA mutations associated with prognosis.

19 citationstop 3%

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsVision ResearchPeer-reviewedNov 30, 2023

Mapping the daily rhythmic transcriptome in the diabetic retina

Ryan Silk, Hanagh Winter, Ouria Dkhissi‐Benyahya…·Eleni Beli

This study examines how diabetes affects the daily rhythmic gene expression in retinas, finding phase shifts in the transcriptional cycle linked to metabolic and hypoxia pathways.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky