Author

Sílvia Carvalho

Universidade do PortoORCID 0000-0001-6436-205XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:experimental assay· 1

Frequent Co-Authors

Alexander KukaleviD· 3 shared Ana PomboiD· 3 shared Luna Zea-RedondoiD· 3 shared Dominik SzabóiD· 2 shared Lonnie R. WelchiD· 2 shared Ana M. Fernandes· 1 shared Ana Rita GrossoiD· 1 shared Anja WeiseiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Alexander KukalevORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 13, 2025

Specialised super-enhancer networks in stem cells and neurons

Izabela Harabula, Liam Speakman, Francesco Musella…·Ana Pombo

The paper compares super-enhancer networks in embryonic stem cells and dopaminergic neurons, revealing their structural differences and functional roles in transcriptional regulation.

DOI 10.1101/2025.08.13.670083

humanChIP-seq

𝕏 PostBluesky

Developmental BiologyBiology OpenPeer-reviewedApr 15, 2024

SRRM2 splicing factor modulates cell fate in early development

Sílvia Carvalho, Luna Zea-Redondo, Tsz Ching Chloe Tang…·Ana Pombo

This study shows that SRRM2 splicing factor dosage affects embryonic stem cell pluripotency and lineage commitment, with implications for developmental diseases and tumorigenesis.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintOct 19, 2022

3D genome topologies distinguish pluripotent epiblast and primitive endoderm cells in the mouse blastocyst

Gesa Loof, Dominik Szabó, Vidur Garg…·Ana Pombo

The paper examines 3D genome structures in mouse blastocyst cells to identify lineage-specific chromatin organization differences between epiblast and primitive endoderm cells.

2 citations

mouseChIP-seq

𝕏 PostBluesky