Author

Hyerim Yi

Howard Hughes Medical InstituteORCID 0000-0001-6456-4743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Howard Y. ChangiD· 2 shared Ivy Tsz-Lo WongiD· 2 shared Jens LuebeckiD· 2 shared King L. HungiD· 2 shared Matthew G. JonesiD· 2 shared Paul S. MischeliD· 2 shared Shu ZhangiD· 2 shared Vineet BafnaiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Howard Y. ChangORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 1, 2025

EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAs

Hyerim Yi, Shu Zhang, Jason T. Swinderman…·Howard Y. Chang

The paper shows that ecDNA-borne PVT1 fusions stabilize oncogenic mRNAs by interacting with SRSF1, enhancing RNA stability and supporting MYC dependency in cancer.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivFeb 15, 2024

CoRAL accurately resolves extrachromosomal DNA genomestructures with long-read sequencing

Kaiyuan Zhu, Matthew G. Jones, Jens Luebeck…·Vineet Bafna

CoRAL improves ecDNA structure reconstruction using long-read sequencing, outperforming short-read methods in simulations and cell-line datasets.

39 citations

humanlong-read sequencing

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