Author

Sophie Clarke

University of ExeterORCID 0000-0001-6464-5578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Sam HughesiD· 2 shared Elsa Florence FouragnaniD· 1 shared Joshua Marquez· 1 shared Mathilde Lojkiewiez· 1 shared Nadège BaultiD· 1 shared Samuel MugglestoneiD· 1 shared Sonia MedinaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Sam HughesORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedMay 9, 2026

Multi-focal ultrasound neuromodulation to the dorsal anterior cingulate cortex disrupts behavioural and neural pain processing

Sophie Clarke, Samuel Mugglestone, Mathilde Lojkiewiez…·Sam Hughes

This study investigates the effects of multi-focal ultrasound neuromodulation on the dorsal anterior cingulate cortex (dACC) in healthy participants, finding delayed analgesic effects and altered neural connectivity related to pain processing.

3 citations

humanimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 30, 2025

Profiling trait and state-like behaviour in pain modulation systems: a role for effective connectivity within endogenous pain control circuits

Sonia Medina, Sophie Clarke, Sam Hughes

This study assesses the test-retest reliability and intra-individual consistency of pain modulation measures and links CPM response variability to effective connectivity in the descending pain modulation system.

1 citation

humanimaging

𝕏 PostBluesky