Multi-focal ultrasound neuromodulation to the dorsal anterior cingulate cortex disrupts behavioural and neural pain processing
Sophie Clarke, Samuel Mugglestone, Mathilde Lojkiewiez, Joshua Marquez, Nadège Bault, Elsa Florence Fouragnan, Sam Hughes
This study investigates the effects of multi-focal ultrasound neuromodulation on the dorsal anterior cingulate cortex (dACC) in healthy participants, finding delayed analgesic effects and altered neural connectivity related to pain processing.
Nature Communications · May 9, 2026Peer-reviewedNeuroscience