BiochemistrybioRxivPreprint
Probing the sequence variability tolerance in a de novo α-helical barrel biocatalyst
Wael Elaily, M. J. BRAUN, David B. Stoll…·Gustav Oberdorfer
This study modifies de novo α-helical barrel biocatalysts using deep learning and computational methods to improve solubility and catalytic performance while maintaining structural stability.
DOI 10.64898/2026.09.28.754888