Author

Birgit Grill

Graz University of TechnologyORCID 0000-0003-1084-3063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1

Frequent Co-Authors

David B. StolliD· 2 shared Gustav OberdorferiD· 2 shared Matteo AleottiiD· 2 shared Mélanie HalliD· 2 shared Morakot ChakatokiD· 2 shared Wael ElailyiD· 2 shared Aleksandar BijeliciD· 1 shared Horst LechneriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 34 mutual co-author links

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2 shared papersBiochemistry

David B. StollORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 29, 2026

Probing the sequence variability tolerance in a de novo α-helical barrel biocatalyst

Wael Elaily, M. J. BRAUN, David B. Stoll…·Gustav Oberdorfer

This study modifies de novo α-helical barrel biocatalysts using deep learning and computational methods to improve solubility and catalytic performance while maintaining structural stability.

DOI 10.64898/2026.09.28.754888

E. coliprotein structure

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 7, 2024

Computational design of a thermostable α-helical barrel protein with tunable active-site positioning

Wael Elaily, David B. Stoll, Morakot Chakatok…·Gustav Oberdorfer

The paper designs and characterizes a thermostable α-helical barrel protein with tunable active-site positioning, showing improved catalytic efficiency.

4 citations

protein structuredeep learning

𝕏 PostBluesky