Author

Andrew W. McCaskie

University of CambridgeORCID 0000-0001-6476-0832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Eleftheria ZegginiiD· 3 shared Jeremy Mark WilkinsoniD· 3 shared Julia SteinbergiD· 3 shared Jyoti Sharma ChoudharyiD· 2 shared Karan Mehul ShahiD· 2 shared Lorraine SouthamiD· 2 shared Matthew J. R. ClarkiD· 2 shared Raveen L. JayasuriyaiD· 2 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Eleftheria ZegginiORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 31, 2020

Decoding the genomic basis of osteoarthritis

Julia Steinberg, Lorraine Southam, Natalie C. Butterfield…·Eleftheria Zeggini

This study identifies molecular subgroups of osteoarthritis and develops a 7-gene classifier to stratify patients, while uncovering potential therapeutic compounds.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedMar 20, 2018

The genetic architecture of osteoarthritis: insights from UK Biobank

Eleni Zengini, Konstantinos Hatzikotoulas, Ioanna Tachmazidou…·Eleftheria Zeggini

This study identifies 9 new osteoarthritis loci using UK Biobank data and finds causal effects of higher body mass index on osteoarthritis.

320 citationstop 1%

humanGWAS summary statistics

𝕏 PostBluesky

Systems BiologyScientific ReportsPeer-reviewedAug 15, 2017

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

Julia Steinberg, Graham R. S. Ritchie, Theodoros I. Roumeliotis…·Eleftheria Zeggini

The paper identifies 49 genes and pathways associated with osteoarthritis progression using integrative epigenomics, transcriptomics, and proteomics in human chondrocytes from OA patients.

118 citationstop 1%

humanDNA methylation

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