Matthew J. R. Clark

This study identifies molecular subgroups of osteoarthritis and develops a 7-gene classifier to stratify patients, while uncovering potential therapeutic compounds.

This study identifies CASC20 and KIF26B as genetic loci associated with heterotopic ossification through genome-wide association and functional analyses.

The paper identifies 49 genes and pathways associated with osteoarthritis progression using integrative epigenomics, transcriptomics, and proteomics in human chondrocytes from OA patients.

This paper conducts a genome-wide association study on developmental dysplasia of the hip using national clinical audit data, identifying genetic loci associated with the condition and demonstrating a scalable recruitment strategy.