Cancer BiologybioRxivPreprint
Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells
Takahide Nejo, Payal B. Watchmaker, Milos Simic…·Hideho Okada
This paper develops a spike-in probe-enhanced scRNA-seq method to track and profile synNotch-CAR-T cells in vivo, revealing tissue-specific activation and transcriptional states.