Author

Heather L. Benway

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aishi Zhao· 2 shared Akane YamamichiiD· 2 shared Hideho OkadaiD· 2 shared Jianwen LuiD· 2 shared Marco GallusiD· 2 shared Payal B. WatchmakeriD· 2 shared Senthilnath LakshmanachettyiD· 2 shared Takahide NejoiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Aishi Zhao

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2 papers

Recent·Most cited

Ultrasound-mediated blood-brain barrier modulation enhances T-cell access but requires immune activation for effective CNS immunity

Marco Gallus, Akane Yamamichi, Victor Andrés Arrieta, Takahide Nejo, Lan Phùng, Atsuro Saijo, Pavlina Chuntova, Jianwen Lu, Su Myat Phyu, Heather L. Benway, Aishi Zhao, Kaori Okada, Payal B. Watchmaker, Jeffrey Haegelin, Senthilnath Lakshmanachetty, , Hideho Okada

This study shows that ultrasound-mediated BBB modulation alone does not generate effective CNS immunity, but combining it with systemic immune activation enhances T-cell responses and improves immunotherapy efficacy.

bioRxiv · Aug 19, 2026 · PreprintImmunology

Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells

Takahide Nejo, Payal B. Watchmaker, Milos Simic, Akane Yamamichi, Senthilnath Lakshmanachetty, Aishi Zhao, Jianwen Lu, Marco Gallus, Heather L. Benway, Robert Zhu, Ricardo Almeida, Wendell A. Lim, Hideho Okada

This paper develops a spike-in probe-enhanced scRNA-seq method to track and profile synNotch-CAR-T cells in vivo, revealing tissue-specific activation and transcriptional states.

bioRxiv · Mar 29, 2026 · PreprintCancer Biology