Author

Rajendra Kumar Gurumurthy

Max Planck Institute for Infection BiologyORCID 0000-0001-6479-8080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Cindrilla ChumduriiD· 3 shared Christian WentlandiD· 2 shared Naveen KumariD· 2 shared Pon Ganish PrakashiD· 2 shared Thomas F. MeyeriD· 2 shared André P. Mäurer· 1 shared Antoine‐Emmanuel SalibaiD· 1 shared Bertram J. WiedenmanniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersSystems Biology

Cindrilla ChumduriORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 13, 2025

Single-cell atlas of patient-derived cervical organoids uncovers epithelial immune heterogeneity and intercellular crosstalk during Chlamydia infection

Pon Ganish Prakash, Naveen Kumar, Stefanie Koster…·Cindrilla Chumduri

This study constructs a single-cell atlas of cervical organoids during Chlamydia infection, revealing epithelial immune heterogeneity and intercellular communication changes.

DOI 10.1101/2025.04.13.648603

humanscRNA-seq

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BioinformaticsBMC BioinformaticsPeer-reviewedOct 21, 2022

Single Object Profiles Regression Analysis (SOPRA): A novel method for analyzing high content cell-based screens

Rajendra Kumar Gurumurthy, Klaus‐Peter Pleißner, Cindrilla Chumduri…·André P. Mäurer

SOPRA is a method for analyzing high-content screens by regressing non-averaged cell feature data to identify significant changes in cell populations.

1 citation

imagingstatistical model

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Developmental BiologybioRxivPreprintAug 5, 2021

Spatial organisation and homeostasis of epithelial lineages at the gastroesophageal junction is regulated by the divergent Wnt mucosal microenvironment

Naveen Kumar, Rajendra Kumar Gurumurthy, Pon Ganish Prakash…·Cindrilla Chumduri

The paper identifies the spatial organisation and regulatory mechanisms of epithelial lineages at the gastroesophageal junction using multi-omics approaches and shows that Wnt microenvironments maintain homeostasis without lineage plasticity.

4 citations

humanbulk RNA-seq

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