Thomas F. Meyer

This study investigates how infection and pesticide exposure lead to α-Synuclein Ser129 phosphorylation through c-Abl kinase activation and identifies potential therapeutic targets.

This study shows that inhibiting ADAM17 enhances cisplatin's cytotoxic effect in cervical cancer spheroids and organoids, suggesting ADAM17 as a potential target for overcoming chemoresistance.

The paper maps DNA methylation and transcriptomes across human stomach regions, showing limited transcriptomic regulation by methylation and identifying region-specific transcription factors.

SOPRA is a method for analyzing high-content screens by regressing non-averaged cell feature data to identify significant changes in cell populations.

The paper identifies the spatial organisation and regulatory mechanisms of epithelial lineages at the gastroesophageal junction using multi-omics approaches and shows that Wnt microenvironments maintain homeostasis without lineage plasticity.

The paper uses bulk and single-cell transcriptomics to analyze SARS-CoV-2 infection in human cell lines, identifying HSP90 as a potential therapeutic target.

The paper identifies ALPK1 and TIFA as key components of an innate immune response triggered by H. pylori's T4SS, independent of CagA translocation.